In a nutshell, the very top layer of your skin is the epidermis, and the topmost layer of that is the stratum corneum. This topmost layer provides a barrier, keeping moisture in and environmental irritants out.1 In atopic dermatitis, this topmost layer is deficient in some of its key components – the particularly ceramides – so it struggles to keep moisture trapped inside. Atopic dermatitis is commonly referred to as eczema.2
"Lipid ratio. The lipid matrix that holds the barrier layer together is made up of 40-50% ceramides, but it also contains cholesterol (25%) and free fatty acids (10–15%).3 These three lipids are needed to maintain the barrier layer.4"
Research has shown that adding ceramides to moisturisers and can help manage dryness and itchiness of helps to improve eczema-prone skin.
"What do ceramide products do?
One study investigated the use of a ceramide-containing moisturiser and cleanser in people with atopic dermatitis.5 They were instructed to use both a ceramide-containing moisturiser and a ceramide-containing cleanser twice a day for six weeks.
Adding ceramides to moisturisers and can help manage dryness and itchiness of eczema-prone skin. Which is why Ego has worked so hard to develop a ceramide-containing moisturiser and cleanser specially formulated to help people with dry, itchy, eczema-prone skin."
1) Cork MJ. The importance of skin barrier function. J Dermatol Treat. 1997; 8: S7 - S13.
2) BetterHealthChannel. Eczema (atopic dermatitis) [Internet]. [updated 2018 Apr; cited 2018 Dec 17]. Available from: https://www.betterhealth.vic.gov.au/health/ConditionsAndTreatments/eczema-atopic-dermatitis
3)Sajic D, Asiniwasis R, Skotnicki-Grant S. A Look at Epidermal Barrier Function in Atopic Dermatitis: Physiologic Lipid Replacement and the Role of Ceramides. Skin Therapy Lett. 2012; 17(7):6-9.
4)Zeichner JA, Del Rosso JQ. Multivesicular Emulsion Ceramide-containing Moisturizers: An Evaluation of Their Role in the Management of Common Skin Disorders. J Clin Aesthet Dermatol. 2016;9(12):26–32.
5)Man MQ M, Feingold KR, Thornfeldt CR, Elias PM, Optimization of Physiological Lipid Mixtures for Barrier Repair. J Invest Dermatol. 1996; 106(5):1096–1101.
6)Lynde CW, Andriesson A. A Cohort Study on a Ceramide-Containing Cleanser and Moisturizer Used for Atopic Dermatitis. Cutis. 2014; 93(4): 207 - 213.